Jul
3rd
2018
My mutants have phenotypes! · 3:49am Jul 3rd, 2018
I am very pleased. My hypothesis appears to be correct!
Deleting Bcat from the Lgr5-expressing cells in the nasopharngeal primodium results in a huge bilateral cleft palate by embryonic day 15.0. But, it would allow the mice to breathe, so this explains why I have some adult Bcat mutants
Deleting the Lgr5 from the Lgr5-expressing cells from this region results in choanal atresia and a slowly-fusing cleft palate with variable gaps.
